Learning Objectives
Upon completion of this activity, participants should be able to:
- List steps in the hepatitis C virus (HCV) life cycle that present opportunities for therapeutic intervention
- Discuss emerging efficacy and safety data on small-molecule specifically targeted anti-HCV agents
- Describe the current understanding of resistance mutations with new therapies
Topics covered include:
- Introduction
- Agents That Block Cell Entry
- Blocking HCV RNA Transport
- Viral Protease Inhibitors
- Viral Polymerase Inhibitors and Other Inhibitors of Transcription
- Inhibition of Virus Assembly and Release
- Conclusions
- Summary: Implications for Clinical Practice