Learning Objectives
Upon completion of this activity, participants should be able to:
- Describe the risk factors for and incidence of depression during interferon-based treatment for HCV infection
- Discuss management strategies for depression in hepatitis C patients, including pretreatment assessment, prevention, and treatment
- Recount the effects of HCV infection and treatment on cognition, sleep patterns, and mood
- Describe the management of psychiatric disorders in hepatitis C patients with concurrent drug addiction
Topics covered include:
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Introduction
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Depression and Interferon alfa Treatment for HCV
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Risk Factors for Neuropsychiatric Adverse Effects
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Depression and Virologic Response
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Pretreatment Assessment of Psychiatric Adverse Events
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Pharmacological Treatment of Depression
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Safety Aspects of Antidepressant Treatment
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Preemptive Therapy With Antidepressants
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Cognition, HCV Infection, and Treatment
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Risk Factors, Diagnosis, and Management of Cognitive Impairment
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Sleep Disturbances, Irritability, and Other Symptoms During Interferon Treatment
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HCV Patients With Psychiatric Disorders in the Setting of Drug Addiction
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Treatment Outcomes in Patients With Psychiatric Disorders and/or Drug Addiction
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Clinical Management of HCV Therapy in Psychiatric Risk Patients
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Summary and Conclusions
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References