Expert Analysis

Resistance and Management of Treatment-Experienced Patients

Source: CCO Official Conference Coverage of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention

Resistance and Management of Treatment-Experienced Patients

Faculty:

W. David Hardy, MD
Charles B. Hicks, MD
William G. Powderly, MD

CME CREDIT INFORMATION

Release Date: 09/28/07

Expiration Date: 09/27/08

Physicians: maximum of 1.25 AMA PRA Category 1 Credits™

Registered Nurses: 1.3 Nursing CE credits

Pharmacists: 1.3 contact hours (0.13 CEUs)

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Learning Objectives

Upon completion of this activity, participants should be able to:

Discuss new insights into the impact of baseline resistance on response to antiretroviral therapy, both in treatment-naive and treatment-experienced patients
Summarize the findings of recent studies of new antiretroviral agents in existing and novel classes in the management of treatment-experienced patients
Describe recent observations regarding the selection of resistance mutations in patients with virologic failure in clinical studies of antiretroviral agents

Topics covered include:

Influence of Baseline Resistance on Antiretroviral Response Rates
TITAN: Comparison of Darunavir/Ritonavir vs Lopinavir/Ritonavir in Treatment-Experienced, Lopinavir-Naive Patients
DUET: Efficacy of Etravirine in Treatment-Experienced Patients
Efficacy and Resistance Emergence With CCR5 Antagonists
Integrase Inhibitors: Efficacy and Cross-Resistance
AVX-201: Apricitabine vs Lamivudine in Treatment-Experienced Patients With the M184V Mutation
Summary and Conclusions

Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.