Module

Eradication of HIV: Possible or Still a Pipe Dream?

Source: HIV/AIDS Annual Update 2008

Eradication of HIV: Possible or Still a Pipe Dream?

Faculty:
Jerome A. Zack, PhD Stephen T. Park, MD, PhD

CME CREDIT INFORMATION

Release Date: 05/20/08

Expiration Date: 05/19/09

Physicians: maximum of 0.75 AMA PRA Category 1 Credit(s)™

Registered Nurses: 0.8 Nursing CE credit

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Learning Objectives

Upon completion of this activity, participants should be able to:

Discuss the clinical significance of the reservoir of latently infected memory CD4+ T cells in HIV-1 infection
Describe the mechanisms responsible for the stability of the latent reservoir
Summarize previous clinical studies and future strategies aimed at eradicating the latent reservoir

Topics covered include:

Introduction
Viral Dynamics After HAART, the Eradication Hypothesis, and the Latent Reservoir
Maintenance of Latency
Dynamics of the Latent Reservoir in Patients on HAART
Strategies to Eradicate the Latent Reservoir: Clinical Studies
Future Immune Activation Therapies
Conclusion
Summary: Implications for Clinical Practice

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